eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | polycystic ovary syndrome |
| Comorbidity | C0206081|hyperandrogenism |
| Sentences | 72 |
| PubMedID- 23355936 | She was affected by hyperinsulinism, hyperandrogenism, amenorrhea, ultrasound signs of polycystic ovarian syndrome (pcos), hypertension with left ventricular hypertrophy as co-morbidities. |
| PubMedID- 25565293 | Context: adrenal hyperandrogenism affects around 25% of polycystic ovary syndrome (pcos) patients but its relation to obesity is not totally understood. |
| PubMedID- 26034121 | Hirsutism induced by hyperandrogenism can be associated with polycystic ovary syndrome, 21-hydroxylase (oh) deficiency or androgen-secreting tumors, including ovarian and adrenal tumors. |
| PubMedID- 25591557 | Identification of differentially expressed micrornas in the ovary of polycystic ovary syndrome with hyperandrogenism and insulin resistance. |
| PubMedID- 20146169 | polycystic ovary syndrome (pcos) is associated with hyperandrogenism, insulin resistance (ir), and chronic inflammation. |
| PubMedID- 25798434 | This case demonstrated that in pcos patients with hyperandrogenism caused by ar gene mutations, their genetic defects can be inherited to their offspring and lead to the development of ais. |
| PubMedID- 24152688 | Context: statins have been shown to improve hyperandrogenism in women with polycystic ovary syndrome (pcos). |
| PubMedID- 24163207 | The purpose of this study is to evaluate whether tanshinone has a significant effect on hyperandrogenism in women with pcos and to explore new uses for cryptotanshinone, the primary biologically active form of tanshinone. |
| PubMedID- 24895496 | Ovarian hyperandrogenism is a hallmark of polycystic ovary syndrome (pcos) and insulin resistance (ir) is a common finding in these women [1–3]. |
| PubMedID- 22091305 | Likewise, in pcos women with hyperandrogenism, the mets prevalence differed among those with or without polycystic ovary (23.1% and 63.8%, respectively; p = 0.001). |
| PubMedID- 23194004 | Effects of metformin on serum insulin and anti-mullerian hormone levels and on hyperandrogenism in patients with polycystic ovary syndrome. |
| PubMedID- 22522778 | Aim: we aimed to compare the effects of metformin and metformin-rosuvastatin combination therapies on hyperandrogenism in patients with polycystic ovary syndrome (pcos). |
| PubMedID- 23873424 | Anovulating pcos patients with severe hyperandrogenism, insulin resistance and hyperinsulinaemia should not be qualified for recfsh ovarian stimulation. |
| PubMedID- 21752527 | It seems that amh level may be used not only as new surrogate marker of ovarian hyperandrogenism in pcos but also as a potential new cardiovascular risk factor. |
| PubMedID- 23216997 | The aim of the study was to determine whether adrenal gland function varies among pcos phenotypes, women with hyperandrogenism (h) only and healthy women. |
| PubMedID- 21177795 | hyperandrogenism in women with polycystic ovary syndrome persists after menopause. |
| PubMedID- 23450052 | Background: polycystic ovary syndrome (pcos) is associated with hyperandrogenism and insulin resistance. |
| PubMedID- 26476820 | Due to the characteristics of hyperandrogenism in polycystic ovary syndrome (pcos), it is plausible that women with pcos may have increased pelvic floor muscle (pfm) thickness and neuromuscular activity levels compared with controls. |
| PubMedID- 22651247 | The hyperandrogenism in women with polycystic ovary syndrome is frequently, but not consistently, associated with increased total and abdominal adiposity [40-42]. |
| PubMedID- 26295295 | Obesity, insulin resistance (ir), inflammation, and hyperandrogenism may lead to polycystic ovary syndrome (pcos) and hypertension. |
| PubMedID- 24606085 | Context: hyperandrogenism is a hallmark of polycystic ovary syndrome (pcos) in women with irregular menses, yet the relationship between androgens and ovarian dysfunction remains poorly understood in eumenorrheic women. |
| PubMedID- 25595199 | pcos phenotypes with hyperandrogenism (a, b and c) have the worst metabolic presentations in terms of ir and mets. |
| PubMedID- 21228310 | Small trials also suggest that metformin has a positive impact on insulin resistance and hyperandrogenism in patients with polycystic ovary syndrome (36,37) or precocious pubarche (38,39). |
| PubMedID- 25246891 | Correlation of biochemical markers and clinical signs of hyperandrogenism in women with polycystic ovary syndrome (pcos) and women with non-classic congenital adrenal hyperplasia (ncah). |
| PubMedID- 21986157 | Hirsutism score and the severity of hyperandrogenism associated with polycystic ovary syndrome in the southeastern region of turkey. |
| PubMedID- 25558892 | Successive, not unsuccessive, ocp cyclical pretreatment could improve pregnancy outcome of pcos patients, associated with reduction of hyperandrogenism and antral follicle excess. |
| PubMedID- 25887459 | In addition, pcos is also associated with hyperandrogenism, menstrual dysfunction, oligo-ovulation and insulin resistance [6]. |
| PubMedID- 23155436 | hyperandrogenism is characteristic of women with polycystic ovary syndrome (pcos). |
| PubMedID- 25006485 | Although chronic hyperandrogenism, a typical feature of polycystic ovary syndrome, is often associated with disturbed reproductive performance, androgens have been shown to promote ovarian follicle growth in shorter exposures. |
| PubMedID- 20036327 | Insulin and hyperandrogenism in women with polycystic ovary syndrome. |
| PubMedID- 21622477 | Single nucleotide polymorphisms (snps) in hsd11b1, the gene encoding 11beta-hsd1, have been associated with type 2 diabetes and hypertension in population-based cohort studies, and with hyperandrogenism in patients with the polycystic ovary syndrome (pcos). |
| PubMedID- 24816764 | Hirsutism and acne resulting from hyperandrogenism in patients with pcos are strongly associated with a person' dissatisfaction with their body and depression [22], indicating a link between hyperandrogenism and depression among women with pcos. |
| PubMedID- 24079935 | Pioglitazone improves peripheral insulin resistance, ovulation, and hyperandrogenism in women with pcos [42-44]. |
| PubMedID- 22086521 | Objectives: the pelvic floor muscles are sensitive to androgens, and due to hyperandrogenism, women with polycystic ovary syndrome can have increased mass in these muscles compared to controls. |
| PubMedID- 25246913 | For diagnosis of pcos, other cause of hyperandrogenism should be rule out including: congenital adrenal hyperplasia, cushing's syndrome, hyperprolactinemia, hypothyroidism and tumors that secrete androgens were excluded by laboratory markers including 17 α hydroxy progesterone, acth test in suspicious cases, prolactin, cortisol level after overnight dexamethasone and thyroid test. |
| PubMedID- 23745331 | pcos is a cause of hyperandrogenism and menstrual disorders with chronic anovulation. |
| PubMedID- 24250624 | Metformin treatment can cause improvements in insulin resistance and ovarian hyperandrogenism in women with pcos (4). |
| PubMedID- 25918588 | The other effectof hyperandrogenism in pcos pregnantpatients at the early embryonic stage has beenproposed as a developmental etiology for pcosin female fetus (27). |
| PubMedID- 26327890 | The available research suggests that hyperandrogenism featuring women with polycystic ovary syndrome (pcos) during their reproductive life persists also after menopause. |
| PubMedID- 24020646 | Suggested that hyperandrogenism in follicular fluid of women with polycystic ovary syndrome inhibited the expression of aqp9 in granulosa cells through the pi3k pathway [6]. |
| PubMedID- 22837189 | polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic pcos phenotypes and healthy controls, independent of obesity and insulin resistance. |
| PubMedID- 22752961 | We propose that hyperandrogenism in pcos may exert an anti-inflammatory effect when obesity is present, but may not promote inflammation in the disorder; and that circulating androgens have a pleiotropic effect on inflammation depending on the combination of pcos and weight status in a given individual. |
| PubMedID- 23575700 | Introduction and hypothesis: hyperandrogenism in women with polycystic ovary syndrome (pcos) could increase muscle mass and thereby pelvic floor muscle (pfm) strength, reducing the risk of urinary incontinence (ui). |
| PubMedID- 23506275 | Methods: this prospective observational study included 59 infertile women: (a) 22 pcos with hyperandrogenism (ha) and oligo-anovulation, (b) 15 suspected pcos with either ha or oligo-anovulation and (c) 22 asymptomatic control women. |
| PubMedID- 20964873 | Finally, pcos with hyperandrogenism group and pcos without hyperandrogenism: group, we assessed total testosterone, 2.8 nmol/l was used as a cutoff point. |
| PubMedID- 24803986 | Ovarian aging-like phenotype in the hyperandrogenism-induced murine model of polycystic ovary (pco) is a new topic. |
| PubMedID- 24842895 | Participants/materials, setting, methods: a group of 20 overweight/obese pcos women with anovulation, hyperandrogenism and polycystic ovaries were subjected to a combined diet and exercise program for 3 months. |
| PubMedID- 20378617 | Background: the present study was designed to evaluate whether the alteration of aquaporin-9 (aqp-9) expression in granulosa cells (gcs) of patients with polycystic ovary syndrome (pcos) was associated with the hyperandrogenism in follicular fluid (ff). |
| PubMedID- 22421986 | Differential diagnosis of hyperandrogenism in women with polycystic ovary syndrome. |
| PubMedID- 24594504 | hyperandrogenism in pcos may also be a function of increased production of biologically active retinoids by theca cells [135]. |
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